Yes, you can, but you may want to reconsider whether you should. Disinheriting a child can lead to a will contest and the dissipation of estate assets in litigation. Even if there is no will contest, disinheriting one or more children is likely to lead to strained family relationships, something you probably do not want. Discuss with your estate planning attorney your reasons for wanting to disinherit one child. She may be able to offer you alternatives that will achieve your goals without creating strife in the family.